Successful Growth of Functional Thymus Organoids from Human Stem Cells

illustration representing the thymus gland

The thymus, a crucial organ for adaptive immune response, produces T cells that attack invaders. With age and certain diseases, the thymus degrades, affecting immunity. Scientists from the University of Florida have grown functional thymus organoids from human stem cells for the first time, potentially aiding the development of patient-specific therapies for thymic dysfunction. Although […]

Lyell Immunopharma Presents First in Human Trial Design of LYL797 at ESMO 2022

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SOUTH SAN FRANCISCO, Calif., Sept. 12, 2022 (GLOBE NEWSWIRE) — Lyell Immunopharma, Inc. (Nasdaq: LYEL), a clinical‑stage T-cell reprogramming company dedicated to developing curative cell therapies for patients with solid tumors, announced today that a poster describing the first-in-human Phase 1 trial design for LYL797, Lyell’s ROR1-targeted CAR T-cell therapy enhanced with genetic and epigenetic […]

The Impact of T Cells in Neurodegenerative Disease and Regenerative Therapies

The Impact of T Cells in Neurodegenerative Disease and Regenerative Therapies

UCI Sue and Bill Gross Stem Cell Research Center Lecture by Craig Walsh, Ph.D. talking a little bit about the immune system and how particular types of cells of the immune system called T cells; the roles that they play in neurodegenerative diseases, and talk about multiple sclerosis and Alzheimer’s disease. And in particular how […]

NexImmune Announces Preclinical Research Collaboration with Columbia University Irving Medical Center’s Herbert Irving Comprehensive Cancer Center

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GAITHERSBURG, Md., April 26, 2022 (GLOBE NEWSWIRE) — NexImmune, Inc. (Nasdaq: NEXI), a clinical-stage biotechnology company developing a novel approach to immunotherapy designed to orchestrate a targeted immune response by directing the function of antigen-specific T cells, today announced a preclinical research collaboration with Columbia University Irving Medical Center’s (CUIMC) Herbert Irving Comprehensive Cancer Center (HICCC). The […]