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Exploring Stem Cell Types in Orthopedic Care: A Breakdown with Dr. Chris Centeno

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In the rapidly evolving field of regenerative medicine, stem cell therapy has emerged as a promising avenue for treating a variety of orthopedic conditions. However, the landscape of stem cell therapy is complex and often misunderstood, with various types of therapies and sources of stem cells adding to the confusion.

In an effort to demystify this topic, we turn to an expert in the field, Dr. Chris Centeno, who has dedicated his career to understanding and advancing the use of stem cell therapies in orthopedic care. In a comprehensive video, Dr. Centeno breaks down the differences between various stem cell therapies, providing invaluable insights into this cutting-edge medical field.

Whether you’re a medical professional, a patient considering stem cell therapy, or simply someone interested in the future of medicine, this blog post will guide you through the intricate world of stem cell therapies in orthopedics. Let’s dive in.

Credit: Chris Centeno, M.D.

Video Summary

In the video, Dr. Centeno reviews a large amount of research to illustrate the differences between the types of therapies used for orthopedic problems that are referred to as stem cells. He reviews Bone Marrow Concentrate (BMC), Micro Fragmented Fat (MFat), Stromal Vascular Fraction (SVF), culture-expanded bone marrow and adipose Mesenchymal Stem Cells (MSCs), umbilical cord Wharton’s Jelly, Cord Blood, and Amniotic derived products.

Dr. Centeno starts by explaining his background and the role of stem cells in the body. He describes stem cells as a general contractor who can call in subcontractors to get the repair job done and then ideally turn into the bricks and mortar, a process called differentiation. He also explains that stem cells or progenitor cells live in every tissue of the body and this is how the body fixes small amounts of local damage.

He then dives into the specific types of products that are out there, starting with autologous cell types like bone marrow concentrate and culture-expanded MSCs. He also discusses adipose-based therapies like finely chopped up fat graft called m-fat, stromovascular fraction, and culture-expanded MSCs.

Dr. Centeno then moves on to allogenic stem cells, discussing Wharton’s jelly and cord blood. He also talks about amniotic derived products including amniotic fluid and placental tissue. He explains each of these types in detail, discussing their benefits, limitations, and legality in the United States.

In summary, Dr. Centeno emphasizes that it takes a village of cells to repair tissue and that those cells need to be close to the type of tissue you want repaired. He concludes by stating that bone marrow and adipose cell therapies are the most used in the United States by legit providers, and explains why fringe providers are focused on more birth tissue derived cells.

This video is a comprehensive guide for anyone interested in understanding the different types of stem cell therapies used in orthopedic care.

*** All content on is for informational purposes only. All medical questions and concerns should always be consulted with your licensed healthcare provider.

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