FDA Approves First CAR-T Therapy for Rare Lymphoma
For patients with relapsed or refractory marginal zone lymphoma (MZL), treatment options have been limited. This rare, slow-growing blood cancer often leaves patients with few paths forward after initial therapies fail. But on December 4, 2025, the U.S. Food and Drug Administration (FDA) announced a landmark decision that offers new hope: the approval of Breyanzi (lisocabtagene […]
Big Nova’s $3M Gift to NMDP Boosts Blood Stem Cell Transplants
A recent $3 million donation from Big Nova to NMDP is a significant step forward in the fight against blood cancer. This gift helps NMDP’s mission to provide life-saving blood stem cell transplants to more patients. This donation also helped NMDP surpass its $100 million fundraising goal. The campaign, which started in 2020, will help thousands of patients […]
A Lab-Grown Bone Marrow to Fight Leukemia?
For decades, leukemia research has been limited by a critical challenge: how do you safely study a disease that originates deep inside our bones? The answer has been a combination of animal models and simplified lab cultures, but both have significant drawbacks. Now, two independent teams of scientists have unveiled a groundbreaking solution: a bioengineered […]
A Lifesaving Gift: 4-Year-Old Transplant Recipient Meets His Donor
A Meeting of Hope and Gratitude In a moment that captured the hearts of many, 4-year-old William Jones, a brave little boy from Peoria, Illinois, finally met the woman who saved his life. Karissa Piccione, a 23-year-old from Florida, donated her bone marrow to William, who was diagnosed with a rare and life-threatening blood disorder. […]
Can Stem Cell Treatment Cause Cancer?
Are you worried that stem cell therapy might increase your cancer risk? Have you heard conflicting information about the safety of stem cell treatments? Do you wonder if the potential benefits outweigh the cancer risks? These concerns are completely valid. The relationship between stem cells and cancer is complex, and understanding the real risks can […]
How a Stem Cell Transplant Saved Will’s Life After a VEXAS Syndrome Diagnosis
Will, a seasoned professional in the film and television industry, found his life turned upside down in 2023—not by the industry-wide strikes, but by a mysterious and life-threatening illness. That illness was VEXAS syndrome, a rare and recently discovered autoinflammatory condition that nearly claimed his life. Initially plagued by unexplained symptoms such as severe fatigue, […]
FDA Grants RMAT Designation to BrainChild Bio’s CAR-T Therapy for Deadly Pediatric Brain Tumors
The U.S. Food and Drug Administration (FDA) has granted Regenerative Medicine Advanced Therapy (RMAT) designation to BrainChild Bio for its B7-H3 CAR-T cell therapy. This experimental treatment targets aggressive brain tumors in children that currently have no cure. What Is CAR-T Therapy? CAR-T therapy is a form of immunotherapy. It involves modifying a patient’s T […]
Leukemia Patient’s Urgent Search for a Stem Cell Match: How You Can Help Save a Life
Eddie Kaufman, a college sophomore from Roanoke University and native of Lackawanna County, is currently facing one of the biggest battles of his life—leukemia. Diagnosed last summer, Eddie’s condition requires a life-saving stem cell transplant, and his family is now calling on the community to step up and potentially save his life. Understanding Leukemia and […]
Intestinal Cell Regeneration Trigger Identified
Researchers at the University of Colorado Anschutz Medical Campus have identified a crucial biochemical process called H3K36 methylation that acts as a “switch” for intestinal cell regeneration after injury. This process controls whether normal intestinal cells can revert to a regenerative stem cell state. The discovery, published in Nature Cell Biology, reveals that H3K36 methylation must be removed for cells to dedifferentiate and […]
Celularity and BlueSphere Bio Collaborate on Cell Therapy Manufacturing
Celularity Inc., a cellular medicine company, has entered into a collaboration agreement with BlueSphere Bio (BSB).? Celularity will leverage its manufacturing capabilities to produce BSB’s T cell receptor (TCR) T cell therapies.? This partnership will focus on manufacturing and quality control at Celularity’s New Jersey facility for BSB’s therapies, including a treatment for Acute Myelogenous […]